Frost-Bite in the Tibet Mission Force

that very often the more serious results of frostbite are directly due, not to excessive cold but to carelessly applied heat. The pathology of the disease, however, explains this apparent paradox. The prime cause of the condition, however, generally was damp clothing combined with extreme cold. Simple dry cold being seldom a cause of frost-bite by itself. The pathology of the disease is as follows:? First Stage.?The cold causes great contraction of the peripheral arterioles, and the affected part, at first painful, becomes gradually numb.